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coli subjected to treatment with CAZ revealed significant alterations in the concentrations of 43 metabolites, with 14 metabolites upregulated and 29 downregulated (Figure 2C)

Citation63 In a mouse model of septic lung injury, Quercetin increased SIRT1 expression in lung tissue, inhibited NLRP3 inflammasome activation, and reduced the release of pro-inflammatory factors (TNF, IL-1, and IL-6), preventing the up-regulation of nuclear PKM2 in the lung