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Similarly, tobacco exposure also resulted in a significantly higher mRNA expression of PARP, a marker of DNA damage and indicator of apoptosis, 43, 44 suggesting that the more extensive MI in tobacco-exposed rats is also accompanied by an increase in cardiomyocyte apoptosis

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Asian Pac J Cancer Prev 17(9):43674375 Santos S, Silva AM, Matos M, Monteiro SM, lvaro AR (2016) Copper induced apoptosis in Caco-2 and Hep-G2 cells: expression of caspases 3, 8 and 9, AIF and p53